Your duties to protect the health and safety of people affected by your work will not change with Brexit. HSE guidance, health and safety made simple: the basics for your business, will help you to comply with the law. See http://www.hse.gov.uk/simple-health-safety/index.htm You should continue to manage risk in your business in a proportionate way. HSE have made minor amendments to regulations to remove EU references but legal requirements will remain the same as they are now. Health and safety standards will be maintained.